Description:
Regression ensemble of sensillum SST-C with 2 individual models (I14 and I15) used for prediction of spike amplitude of the extracellularly record of ORN response potentials of the antennal trichoid sensilla to Cx. quinquefasciatus repellents.

The training was performed with M5P tree algorithm as default in Weka 3.9.4 with a 10-fold cross-validation. Models I14 and I15 were developed by using 3 and 10 QuBiLS-MIDAS descriptors, respectively, namely:

CHOQUET[D;0.5;AO2;0.6]_Q_AB_nCi_2_M14_SS4_T_LGL[2-5]_e_MID
AC[4]_S_Q_AB_nCi_2_M1_SS7_o_T_LGL[1-2]_a_MID
ES_SD_F_AB_nCi_2_M1_SS1_T_LGP[5]_a_MID
K_TrQB_AB_nCi_3_M19(M1)_NS4_T_KA_m-p_MID
VC_TrF_AB_nCi_3_M21(M1)_SS1_T_LG3L[2-3]_LGL[2-3]_p_MID
MX_Q_AB_nCi_2_M11_MP7_T_LGL[1-2]_v_MID
S_B_AB_nCi_2_M13_NS4_T_LGL[5-6]_a-s_MID
I50_B_AB_nCi_2_M14_NS0_T_LGP[2]_p-h_MID
AC[5]_S_F_AB_nCi_2_M8_SS3_T_LGP[1]_v_MID
K_TrB_AB_nCi_3_M26(M3)_NS3_T_KA_m-p_MID
GV[2]_K_Tr_AB_nCi_3_M22(M8)_SS1_T_KA_m-psa-a_MID
AC[5]_S_B_AB_nCi_2_M3_NS6_o_T_LGP[2]_h-s_MID

Training set:
50 compounds extracted from the Liu, et al., 2013 original experimental research constitute the training set 10.1016/j.jinsphys.2013.08.016

Performance:
For a 10-fold cross-validation, the statistical parameters (performance without applicability domain) are R = 0.9952, MAE = 0.7248, RMSE = 1.6828, RAE = 5.2068 %, and RRSE = 9.5548 %.

Classification Breakpoint:
The breakpoint for sensillum SST-C is 13.5 spikes/s. Values greater than or equal to the breakpoint will elicit a response in this specific sensillum. Lower values represent certain actions occurring, however, they are not enough to activate the sensillum response.

Reference:
Liu et al. Olfactory responses of the antennal trichoid sensilla to chemical repellents in the mosquito, Culex quinquefasciatus. 2013, 59(11), 1169-1177. DOI: 10.1016/j.jinsphys.2013.08.016